• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.


St. Michael's Hospital



Contact This Member

John C. Marshall

John Marshall is a Trauma and Acute Care surgeon and intensivist at St. Michael’s Hospital in Toronto, and a professor of surgery at the University of Toronto.

A member of the Canadian Critical Care Trials Group since its launch in 1989, he has served as its Chair since 2005.  John has an academic interest in sepsis and the multiple organ dysfunction syndrome. He runs a laboratory funded by CIHR and the PSI Foundation that studies the cellular mechanisms underlying prolonged neutrophil survival in trauma and sepsis, and currently supervises two PhD students. As a clinical investigator he has been the principle investigator of the AATICC trial of empiric antibiotic therapy for suspected ICU-acquired infection and of the CHAT trial of adjuvant therapy for H1N1 influenza, as well as a co-investigator on a number of Trials Group programs.  John has also been a steering committee member for a number of industry-sponsored trials of novel therapies for sepsis.   Rising out of his passion for the Trials Group model of investigator-led research, he is the inaugural chair of the International Forum for Acute Care Trialists (InFACT), an umbrella group that brings together the CCCTG and 18 similar sister groups from around the world.  He is an executive committee member of the International Severe Acute Respiratory Infections Consortium, and has previously served as president of the Surgical Infection Society and chair of the International Sepsis Forum.   He has authored more than 250 manuscripts and 80 book chapters, and been an invited speaker at more than 400 national and international symposia.  He is married with one daughter.