• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.


St. Michael’s Hospital



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Karen Burns

Karen Burns practices critical care medicine at St. Michael’s Hospital in Toronto. She is an Assistant Professor of Medicine at the University of Toronto, a Clinician Scientist at the Keenan Research Centre/Li Ka Shing Knowledge Institute and an Associate Member of the School of Graduate Studies with the Institute of Health Policy Management and Evaluation at the University of Toronto.

Dr. Burns has developed a research program focusing on characterizing the extent of weaning practice variation in weaning critically ill adults from invasive mechanical ventilation. This research program includes a bicentre observational study, national and international weaning surveys and a randomized trial of an automated weaning strategy to limit practice variation. In addition, she has developed a research program to characterize the unique aspects of consent processes in critical care and the experience of surrogate decision-makers asked to make substituted judgments regarding a critically ill loved one’s participation in research. Additional research interests include acute kidney injury in the intensive care unit, the role for noninvasive positive pressure ventilation as a weaning strategy and methodology issues in study design, implementation and reporting.