• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.


McMaster University



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Michelle Kho

Dr. Michelle Kho is a Tier 2 Canada Research Chair in Critical Care Rehabilitation and Knowledge Translation in the Faculty of Health Sciences at McMaster University. Her academic home is in the School of Rehabilitation Science at McMaster and her clinical home is the ICU in St Joseph's Healthcare Hamilton.

As a physiotherapist and methodologist, Dr. Kho has designed a vibrant, vigorous program of research focused on improving the rehabilitation of persons recovering from critical illness. The CYCLE Program (Critical Care Cycling to Improve Lower Extremity Strength) is a multi-method and multi-professional program of investigations using a physiological and clinical approach to exercise, which will encourage and examine in-bed cycling for patients on advanced life support. Her CIHR-funded pilot study, TryCYCLE involves both passive and active in-bed cycling for mechanically ventilated patients in Hamilton and eventually elsewhere in Canada. This work of the CCCTG could improve the outcomes of ICU survivors and strengthen rehabilitation research in the field of critical care.