• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.


University of Manitoba



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Ryan Zarychanski

Ryan Zarychanski is a Critical Care physician, Hematologist, and Clinician Scientist at the University of Manitoba and CancerCare Manitoba, and is an active member of the CCCTG.

Ryan Zarychanski completed combined fellowships in Critical Care Medicine and Hematology, (University of Manitoba) followed by Masters degree in Epidemiology and a research fellowship (University of Ottawa) under Drs. Dean Fergusson and Paul Hebert.  Dr. Zarychanski’s research focuses on the hematologic aspects of critical illness. His major research program evaluates the efficacy and safety of unfractionated heparin in septic shock – a program that has evolved, with close collaboration from the CCCTG, into a multicentre randomized controlled trial; the HALO pilot.  Other active programs of research include massive transfusion, assessment of bleeding in the ICU, and thrombocytopenia in critical illness.  Methodological interests include propensity adjusted analysis and network meta-analyses.  Dr. Zarychanski receives operating and salary support from the Canadian Institutes of Health Research (CIHR).