| Programs ▼ | Principal Investigator(s) | Coordinator(s) | Status | |
| WAVE - A Multicenter Evaluation of Altered Heart Rate and Respiratory Rate Variability to Predict Extubation Failure | Andrew Seely | Anna Fazekas | Completed | Learn More |
| VITdAL-PICU - Rapid normalization of vitamin D in critically ill children | Dayre McNally | Katie O’Hearn | Completed | Learn More |
| TOP UP - A Randomized Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients | Daren Heyland
| Rupinder Dhaliwal (Project Leader) and Maureen Dansereau (Project Assistant) | Enrolling | Learn More |
| THRRIVES - Temperature, Heart and Respiratory Rate Investigation along with Variability Evaluation and Serum Biomarkers Study | Andrew Seely, Christopher Bredeson | Kaitlyn Chambers, Anna Fazekas
| Enrolling | Learn More |
| The REDOXS© Study | | | Published | Learn More |
| The REALISTIC 80 Study | | | Published | Learn More |
| The CANTREAT Study | | | Published | Learn More |
| Teams 4 Kids | Elaine Gilfoyle | Deanna Koot | Enrolling | Learn More |
| TBI-Prognosis | Alexis Turgeon | Lucy Clayton and Caroline Léger | Completed | Learn More |
| SuDDICU - Selective Decontamination of the Digestive Tract in the ICU | Brian Cuthbertson | To be announced | Not Yet Recruiting | Learn More |
| STRIPES — Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock | Kusum Menon | Katie O’Hearn | Completed | Learn More |
| STARRT-AKI – Standard vs. Accelerated Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury | Sean Bagshaw, Ron Wald | Janice Jansen-Pereira | Enrolling | Learn More |
| SPICE - Adverse drug reactions in the critically ill | Yoanna Skrobik | | Enrolling | Learn More |
| SLEAP | Sangeeta Mehta | Lisa Burry | Published | Learn More |
| SHIPSS - Stress Hydrocortisone in Pediatric Septic Shock | Kusum Menon
| Katie O’Hearn | Enrolling | Learn More |
| SEVA - Improving Safety of Sedation Practice and Critical Illness Prognostication | Andrew Seely | Anna Fazekas | Enrolling | Learn More |
| SENIOR Trial- Screening Elderly PatieNts For InclusiOn in a Weaning Trial | Karen Burns
| | Completed | Learn More |
| RELEASE Trial | Karen Burns
| Leena Rizvi | Completed | Learn More |
| RECOVER | Margaret Herridge
| Program Manager: Priscila Robles
Research Coordinators: UHN (TWH)Andrea Matte, Paulina Farias, Cheryl Geen-Smith; MSH - Cheryl Ethier, Maedean Brown, Brittany Giacomino and Sumesh Shah; SMH - Orla Smith, Yoon Lee, Kerri Porretta, Julia Lee and Melissa Wang; SHSC - Nicole Marinoff, Jane Wang, Derek Parsotam and Ashwati Raghunath; SJH - Andrea Tkaczyk and France Clarke; OHSC - Mary-Jo Lewis, Tracey McArdle and Brigette Gomes; SPH - Lynda Lazosky, Ellen Woo; CHUS - Chantal Langevin, Karine Grondi, Joanie Lacasse-Bedard and Eugenie Pinsonnault; HMR: Joanne Harvey | Enrolling | Learn More |
| PROSPECT — Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial | Deborah Cook | Nicole Zytaruk et France Clarke | Enrolling | Learn More |
| PRECISE | Lauralyn McIntyre | | Enrolling | Learn More |
| Plasma Transfusions in Critically Ill Children - Point Prevalence Study | Oliver Karam | To come. | Enrolling | Learn More |
| PIT-TBI | François Lauzier | Lucy Clayton | Enrolling | Learn More |
| OVATION — Optimal VAsopressor TItratiON | François Lamontagne | Chantal Langevin, Janet Overvelde | Enrolling | Learn More |
| OSCILLATE — Oscillation for ARDS Treated Early | Maureen Meade & Niall Ferguson | Lori Hand | Completed | Learn More |
| Knowledge transfer and best practices in emergency medicine and in traumatology: impact of wikis | Patrick Archambault | Carrie Anna McGinn | Enrolling | Learn More |
| IOStudy — International Observational Study | Karen Burns
| Ms. Leena Rizvi, Ms. Kelly Klouvidakis | Enrolling | Learn More |
| Improvement of ventilatory support during pediatric non-invasive ventilation | Guillaume Emeriaud | Nicole Poitras | Enrolling | Learn More |
| HICCUPS - Hypovitaminosis-D In Critically ill Children: Understanding Pathways and Solutions (1) | Dayre McNally | Katie O’Hearn | Not Yet Recruiting | Learn More |
| HEMOTION Trial | Alexis Turgeon, François Lauzier, Dean Fergusson
| | Enrolling | Learn More |
| HALO | Ryan Zarychanski & Dean A Ferguson
| Nicole Marten, Wendy Janz, Ellen McDonald, Suzy Lavoie, Irene Watpool, Tracy McArdle, Orla Smith | Enrolling | Learn More |
| GRASP1 - Global Resource Allocation Survey Project | Michael Christian | Melanie Guenette | Enrolling | Learn More |
| FAST Trial | Karen Burns
| Leena Rizvi | Completed | Learn More |
| EXERCISE - The EXercise and Early Rehabilitation in Critically Ill Children: a Systematic Evaluation Research Program | Karen Choong
| | Enrolling | Learn More |
| DYNAMICS | Patricia Liaw | Ellen McDonald, Irene Watpool, Tracey McArdle, Claude Ferland, Orla Smith, Betty Jean Ashley, Eileen Campbell, Christine Skinner, Josee Wong | Not Yet Recruiting | Learn More |
| DDePICt - Determination of Death Practices in Intensive Care Resarch Program | Sonny Dhanani | Amanda van Beinum | Enrolling | Learn More |
| CYCLE - Critical Care Cycling to Improve Lower Extremity Strength | Michelle Kho | France Clarke | Enrolling | Learn More |
| Canada DONATE | Frederick D'Aragon, Maureen Meade
| Aemal Akhtar, Erika Arseneau, Lori Hand, Marie-Hélène Masse
| Enrolling | Learn More |
| BALANCE — Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness | Nick Daneman & Rob Fowler | A Rishu | Completed | Learn More |
| aC3KTion Net — A Canadian Critical Care Knowledge Translation Network | John Muscedere | Nicole O'Callaghan & Nomusa Mngoma | Not Yet Recruiting | Learn More |
| ABLE - Age of Blood Evaluation Study: a Multicenter Randomized Clinical Trial | Jacques Lacroix, Paul Hébert, Dean Fergusson and Alan Tinmouth | Lucy Clayton | Published | Learn More |
| ABC PICU — Age of Blood in Children PICU | Marisa Tucci | Nicole Poitras & Lucy Clayton | Enrolling | Learn More |