• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.

Principal Investigator(s)

Ryan Zarychanski & Dean A Ferguson


Nicole Marten, Wendy Janz,  Ellen McDonald, Suzy Lavoie, Irene Watpool, Tracy McArdle, Orla Smith




Heparin AnticoaguLation to improve Outcomes in septic shock



St-Boniface Hospital; PI - Ryan Zarychanski, Coordinator - Nicole Marten
Health Sciences Centre; PI - Clare Ramsey, Coordinator - Wendy Janz


Hamilton General Hospital; PI - Alison Fox-Robichaud, Coordinator - Ellen McDonald
St. Joseph’s Healthcare; PI - Deborah Cook, Coordinator - Ellen McDonald

Quebec City

Hôpital de l’Enfant-Jésus; PI - Alexis Turgeon, Coordinator - Suzy Lavoie


The Ottawa Hospital, General Campus; PI - Lauralyn McIntyre, Coordinator - Irene Watpool
The Ottawa Hospital, Civic Campus; PI - Joe Pagliarello, Coordinator - Tracy McArdle


St. Michael’s Hospital; PI - John Marshall, Coordinator - Orla Smith


Participating Centers

St-Boniface Hospital
Health Sciences Centre
Hamilton General Hospital
St. Joseph’s Healthcare
Hôpital de l’Enfant-Jésus
The Ottawa Hospital
St. Michael’s Hospital
Hamilton General Hospital