• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.

Principal Investigator(s)


Rupinder Dhaliwal (Project Leader) and Maureen Dansereau (Project Assistant)



TOP UP - A Randomized Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically


Paul Wischmeyer (US Co-Principal Investigator)

Participating Centers

Royal Alexandra Hospital, Edmonton, Alberta
University Hospital, Edmonton, Alberta
University of Colorado
Grey Nun’s Hospital
Oregon Health Sciences University, Portland, Oregon
University Hospital, Strasbourg, France
Hopital Universitaire Erasme, Brussels, Belgium
University of Texas Health Sciences Center-Houston, Texas
St. John’s Mercy Hospital, St. Louis, US
The Ohio State University Medical Center, US
Washington University School of Medicine in St. Louis, US
Cleveland Clinic, Cleveland, Ohio, US