• Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a highly collegial group that is dedicated to the pursuit of excellence and advancement of critical care research in Canada.
  • Canadian Critical Care Trials Group
    The CCCTG has are more than 30 research programs underway and over 100 peer-reviewed publications to its credit, with direct impact on clinical practice in critical care.
  • Canadian Critical Care Trials Group
    The Canadian Critical Care Trials Group (CCCTG) is a national organization of more than 300 individuals with research interests in the management of the critically ill patient.
  • Canadian Critical Care Trials Group
    Endorsement by the CCCTG communicates our full commitment to ensure that the work is undertaken in a rigorous and ethical manner, and communicated in a timely and effective way.

Principal Investigator(s)


Nicole O'Callaghan & Nomusa Mngoma


Not Yet Recruiting

aC3KTion Net — A Canadian Critical Care Knowledge Translation Network

Knowledge Translation in Canadian Critical Care

Critical care is a vital component of acute care medicine that serves a vulnerable patient population with high morbidity and mortality, is in high demand and consumes large amounts of health care resources. If this expensive and important resource is to be optimally utilized, best practice as informed by research evidence needs to be incorporated into patient care. However, the critical care literature base is rapidly increasing and it is difficult for health care practitioners to remain current, to assimilate and then apply relevant evidence into practice. To overcome this, extensive efforts at knowledge translation (KT) are required.

In Canada, there have been sporadic and limited efforts at improving the assimilation of best practice into critical care units and much of the focus on critical care KT has been on patient safety. For patient outcomes to be improved on a broader scale, all best practices as informed by research evidence need to be considered for KT initiatives in the ICU. The Critical Care Knowledge Translation Network (CCCKTN) seeks to implement a systematic, multifaceted and synergistic knowledge translation strategy. CCCKTN will bring together necessary expertise from across jurisdictions, health care backgrounds and will support an infrastructure to accelerate the translation of research findings into practice in order to improve the care of the critically ill across the Canadian Health Care System.

The objectives of CCCKTN will be as follows:

  1. To bring together critical care researchers and knowledge users (health care professionals, national professional associations, and health care system decision makers) to optimize resources and support collaborative knowledge translation activities.
  2. To survey practice at baseline and after implementation efforts to guide knowledge translation activities and measure the results of our efforts.
  3. To conduct knowledge synthesis activities and develop knowledge products to inform critical care best practices.
  4. To improve the care and outcomes of critically ill patients through the dissemination of best practices, as defined by research evidence, into ICUs across Canada.

The scope of CCCKTN will be as follows:

All critical care units in Canada will be eligible and encouraged to participate in CCCTKN activities. Best practices that will be included in this network will be those pertaining to clinical practice and those related to the organization/administration of critical care resources. We will include multi-professional representation to encompass the multi-disciplinary nature of ICU teams.

Inclusion of relevant stakeholders

CCCKTN will include representation from all aspects of Canadian critical care including provincial administrators, critical care knowledge generators, producers of critical care KT products and those who have experience with the dissemination of best practices to health care professionals. Multi-professional societies will be involved in CCCTKN activities as will organizations that are active in patient safety including the Canadian Patients Safety Institute. Moreover, we have engaged pediatric representation who will be engaged in all aspects of network activities.


John Muscedere, Daren Heyland, Tasnim Sinuff, Peter Dodek, Jacques LaCroix, Deborah Cook, Clarence Chant PharmD, Steven Reynolds, Claudio Martin, Damon Scales, Alexis Turgeon

Participating Centers


Website: www.acktionnet.ca